Liraglutide vs Semaglutide vs GLP-1 for weight loss

If you’ve been in the loop regarding popular weight loss treatments, you’ve likely heard of liraglutide (sold as Saxenda) and Semaglutide (sold as Wegovy). As they both belong to a class of drugs called GLP-1 receptor agonists, Semaglutide and liraglutide work similarly. These medications reduce your appetite to promote weight loss. But with two strong options available, you’re likely wondering: Which one is right for me?

For anyone trying to lose weight, especially when traditional methods like diet and exercise haven’t been enough, choosing the right treatment is essential. Liraglutide and Semaglutide are two great options, so understanding the differences between them, such as their effectiveness, side effects, and costs, is important for making an informed decision.

If you’re currently using liraglutide but feel that you’re not seeing the results you want, or if the daily injections are becoming a hassle, you may be considering a switch to semaglutide. Many people who switch report positive outcomes, including greater weight loss and the convenience of once-weekly injections.

To transition from liraglutide to Semaglutide safely, it’s essential to speak with Dr. Purnima Balla, MD, who will help you change and adjust to your new medication. Additionally, keep in mind that while Semaglutide may cause more intense side effects at the start, like nausea or gastrointestinal discomfort, these tend to subside after a couple of weeks of starting the medication.

For those interested in switching from liraglutide to Semaglutide, the next step is to schedule a visit with a healthcare provider. Your doctor will assess your circumstances and create a plan to help you transition smoothly.

At first glance, liraglutide and Semaglutide may seem very similar, as both belong to the GLP-1 receptor agonist family. That said, there are various key differences between the two medications that may influence which one is right for you.

A key difference between liraglutide and Semaglutide is how often you need to take them. Liraglutide injections are designed to be taken daily. This means you’ll need to give yourself an injection every day, which is a downside for people who don’t like the idea of frequent shots. In contrast, Semaglutide is a once-weekly injection.

In addition, current research highlights that Semaglutide provides greater results in terms of weight loss when compared to liraglutide. Due to this, Semaglutide is the more popular weight-loss medication of the two.

In a major clinical trial called STEP 8, researchers compared the two medications directly. Participants who took Semaglutide lost 15% of their body weight on average, while those who took liraglutide lost around 6%.

Semaglutide effectiveness comes from its stronger formulation and the fact that you only need to take it once a week. This higher dosage means that your body stays in a fat-burning, appetite-suppressing state for longer. The convenience of weekly injections also helps people stick to their treatment plan, which can lead to better long-term results.

The cost of GLP-1 treatments like liraglutide and Semaglutide is often a significant factor for patients when deciding which medication to use. Liraglutide has an average cost of $1,300 per month without insurance, while Semaglutide is typically slightly more expensive, averaging around $1,500 per month. If you have insurance, the cost may be lower, but coverage varies widely depending on your plan, location, and medical history.

While Semaglutide is more expensive, its greater effectiveness provides better value for money. As it’s possible to lose more weight in less time with Semaglutide, it is the more cost-effective treatment approach despite the higher monthly price.

If financial commitment is a major barrier for you when accessing weight loss treatment, our team can support you in exploring savings programs and manufacturer discounts. To have your questions about liraglutide and Semaglutide answered, contact us and schedule your consultation today! We are conveniently located at 3000 E 1st Ave Unit 114, Denver, CO 80206. Call Now or Request an Appointment Online! We serve clients from Denver CO, Ruby Hill Park CO, Park Hill CO, Lakewood CO, Coors Field CO, Edgewater CO, Globeville CO, Village East CO, and surrounding areas.